Interested in this conversation as my modern Bonnies have given me some pain in the .... thought I'd say ASSpirin bottle, didn't you!

The riding postures on the modern Bonnies I've owned create a certain amount of pain in my hands around the 50 mile-ish mark. My 2011 SE had M-bars that created a leaned-over posture, café style of riding. I could see that. (Also caused a bit of pressure on the aging nether regions, truth be told. Frequent stops were thus created.)
Moving on, I see these as a
potentially ride extender device as many times I arrive at a traffic control device finding myself flexing my arms and hands due to strain. I don't know. Some seem to like them, some don't.
My Classics have never, ever given me problems in the handlebar region. The stock, standard titty grips work fine. Seating comfort? My inseam would increase by an inch or two after a lengthy ride. But no other physical attribute alterations. Ish. I used a gel pad. So no other changes that I know of. Of. Of. Of. Of.
Felony mentioned gloves with padding. That's what I've been looking for. With no luck, mind.
A little comfy in the hiney, a lot more comfy in the handlebars, the modern T120 is a dream.
If I order some grippy titty handlebar puppies, I'll let you know how they work out.