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Joe,
I put about 16K (16,000) miles on my last set of Metzeler ME880's. Running 39psi Front / 41 psi Rear. Checking the pressure weekly.
I do commuting and some sport riding on them 80%/20% , they're excellent in the rain and slick roads (winter). Very confidence inspiring for spirited riding as well on dry roads.
For brake pads, I run stock pads in the rear they last about 8K miles, I use EBC's FA188HH on the front with Busa 6 pot calipers. I haven't worn a set out yet.
YMMV,
Andrew
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