Jared26 - From personal experience, touring on the S4 was a whole lot of fun. When I did my cross country trip, I setup my gearing as 15/42 which I believe would be equivalent to 16/45. This eliminated alot of vibration (comfort factor) but took a bit of getting used to since it changed the power band. I would recommend bringing rain gear. Even if they are throwovers, better to be safe than sorry. I travelled with the triumph soft panniers and a submersible bag that I bungied over the back seat. The submersible bag held my sleeping bag and tent while the panniers held consumables and clothes. Go to your local auto parts store and get a tire plug kit. I had to learn the hard way by getting a flat in Florida and the closest bike shop was 2 hours away. Bring some first aid stuff. Go to triumphs site and get a list of all dealers in the states you will be travelling through. That is all that comes to mind right now. Enjoy your trip and be safe
If your heading north, look at Hwy 64 near Taos, NM. There was still snow when I rode through but it is a fun road.